Genesys Cloud WebRTC Media Helper can be configured to operate within Citrix environments using Citrix's Browser Content Redirection feature, which eliminates the need for separate login credentials on local devices outside the virtual desktop infrastructure (VDI). This feature is currently in Limited Availability for the Genesys Cloud European Sovereign Region and supports Windows and Linux workstations only, with MacOS remaining unsupported. The Media Helper must execute on the Citrix client to function properly. Configuration requires editing the Windows registry on the Citrix server to add specific multi-string values in HKEY_LOCAL_MACHINESOFTWARECitrixHDXMediaStream: WebBrowserRedirectionAcl and WebBrowserRedirectionAuthenticationSites, both containing the Genesys Cloud login URL and WebRTC Media Helper app URL for the user's region appended with /*. Additionally, a Chrome Enterprise policy string value named LocalNetworkAccessAllowedForUrls must be added to the same registry location. This policy pre-authorizes WebSocket connections to localhost port 9002 for media offloading and suppresses user permission prompts triggered by recent Google Chrome security updates that modified how browsers handle local resource connections. Registry editing carries inherent risks to operating system stability, and backing up the registry before modifications is recommended as best practice. Genesys Cloud operates across multiple global regions with dedicated access points and region-specific endpoints. The deployment infrastructure spans Americas (US East, US East 2/FedRAMP, US West, Canada, South America, and Mexico), EMEA (Frankfurt, Dublin, London, Zurich, UAE, and European Sovereign Region/Brandenburg), and Asia Pacific (Mumbai, Tokyo, Seoul, Osaka, Singapore, and Sydney) locations. Each region maintains distinct login URLs and WebRTC Media Helper application endpoints, such as login.mypurecloud.com for US East and region-specific variants like login.mypurecloud.de for Frankfurt. The US East 2 region operates under FedRAMP compliance for U.S. Public Sector agencies, while the European Sovereign Region is designed to meet EU data residency and operational autonomy requirements. For troubleshooting, Genesys supports running Genesys Cloud in Citrix environments with WebRTC Media Helper through a structured support pathway. Users encountering issues should contact their Citrix partner, review Citrix Browser Content Redirection documentation, and consult Citrix support resources. The documentation includes a feedback mechanism for reporting inaccurate, incomplete, or outdated information, with additional support available through community forums for unresolved questions.