Genesys Cloud's Global Media Fabric feature allows configuring any Genesys Cloud media region worldwide for real-time client and carrier media streams. It enables prioritizing media regions on the Sites page, associating sites with trunks, and simulating calls to test multi-region media routing. Key capabilities include global media stream management, redundant media processing, and optimizing media traffic based on proximity. Use cases include improving reliability, reducing latency, and localizing media handling.